Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2

Transcriptional-translational feedback loops (TTFLs) are a conserved molecular motif of circadian clocks. The principal clock in mammals is the suprachiasmatic nucleus (SCN) of the hypothalamus. In SCN neurons, auto-regulatory feedback on core clock genes Period (Per) and Cryptochrome (Cry) followin...

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Detalles Bibliográficos
Autores principales: Smyllie, Nicola J., Pilorz, Violetta, Boyd, James, Meng, Qing-Jun, Saer, Ben, Chesham, Johanna E., Maywood, Elizabeth S., Krogager, Toke P., Spiller, David G., Boot-Handford, Raymond, White, Michael R.H., Hastings, Michael H., Loudon, Andrew S.I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963210/
https://www.ncbi.nlm.nih.gov/pubmed/27374340
http://dx.doi.org/10.1016/j.cub.2016.05.018

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