The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis

Recent studies have detailed the genomic landscape of primary endometrial cancers, but their evolution into metastases has not been characterized. We performed whole-exome sequencing of 98 tumor biopsies including complex atypical hyperplasias, primary tumors, and paired abdominopelvic metastases to...

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Detalles Bibliográficos
Autores principales: Gibson, William J., Hoivik, Erling A., Halle, Mari K., Taylor-Weiner, Amaro, Cherniack, Andrew D., Berg, Anna, Holst, Frederik, Zack, Travis I., Werner, Henrica M. J., Staby, Kjersti M., Rosenberg, Mara, Stefansson, Ingunn M., Kusonmano, Kanthida, Chevalier, Aaron, Mauland, Karen K., Trovik, Jone, Krakstad, Camilla, Giannakis, Marios, Hodis, Eran, Woie, Kathrine, Bjorge, Line, Vintermyr, Olav K., Wala, Jeremiah A., Lawrence, Michael S., Getz, Gad, Carter, Scott L., Beroukhim, Rameen, Salvesen, Helga B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963271/
https://www.ncbi.nlm.nih.gov/pubmed/27348297
http://dx.doi.org/10.1038/ng.3602

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