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Emerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disorders

Nicotinamide adenine dinucleotide (NAD(+)) is a central metabolic cofactor in eukaryotic cells that plays a critical role in regulating cellular metabolism and energy homeostasis. NAD(+) in its reduced form (i.e. NADH) serves as the primary electron donor in mitochondrial respiratory chain, which in...

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Detalles Bibliográficos
Autor principal: Srivastava, Sarika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963347/
https://www.ncbi.nlm.nih.gov/pubmed/27465020
http://dx.doi.org/10.1186/s40169-016-0104-7