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Emerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disorders
Nicotinamide adenine dinucleotide (NAD(+)) is a central metabolic cofactor in eukaryotic cells that plays a critical role in regulating cellular metabolism and energy homeostasis. NAD(+) in its reduced form (i.e. NADH) serves as the primary electron donor in mitochondrial respiratory chain, which in...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963347/ https://www.ncbi.nlm.nih.gov/pubmed/27465020 http://dx.doi.org/10.1186/s40169-016-0104-7 |