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Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms
The current treatment of pituitary adenomas requires a balance of conservative management, surgical resection, and in select tumor types, molecular therapy. Acromegaly treatment is an evolving field where our understanding of molecular targets and drug therapies has improved treatment options for pa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963385/ https://www.ncbi.nlm.nih.gov/pubmed/27517036 http://dx.doi.org/10.3389/fsurg.2016.00045 |
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author | Mooney, Michael A. Simon, Elias D. Little, Andrew S. |
author_facet | Mooney, Michael A. Simon, Elias D. Little, Andrew S. |
author_sort | Mooney, Michael A. |
collection | PubMed |
description | The current treatment of pituitary adenomas requires a balance of conservative management, surgical resection, and in select tumor types, molecular therapy. Acromegaly treatment is an evolving field where our understanding of molecular targets and drug therapies has improved treatment options for patients with excess growth hormone levels. We highlight the use of molecular therapies in this disease process and advances in this field, which may represent a paradigm shift for the future of pituitary adenoma treatment. |
format | Online Article Text |
id | pubmed-4963385 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-49633852016-08-11 Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms Mooney, Michael A. Simon, Elias D. Little, Andrew S. Front Surg Surgery The current treatment of pituitary adenomas requires a balance of conservative management, surgical resection, and in select tumor types, molecular therapy. Acromegaly treatment is an evolving field where our understanding of molecular targets and drug therapies has improved treatment options for patients with excess growth hormone levels. We highlight the use of molecular therapies in this disease process and advances in this field, which may represent a paradigm shift for the future of pituitary adenoma treatment. Frontiers Media S.A. 2016-07-28 /pmc/articles/PMC4963385/ /pubmed/27517036 http://dx.doi.org/10.3389/fsurg.2016.00045 Text en Copyright © 2016 Mooney, Simon and Little. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Surgery Mooney, Michael A. Simon, Elias D. Little, Andrew S. Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms |
title | Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms |
title_full | Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms |
title_fullStr | Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms |
title_full_unstemmed | Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms |
title_short | Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms |
title_sort | advancing treatment of pituitary adenomas through targeted molecular therapies: the acromegaly and cushing disease paradigms |
topic | Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963385/ https://www.ncbi.nlm.nih.gov/pubmed/27517036 http://dx.doi.org/10.3389/fsurg.2016.00045 |
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