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Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms

The current treatment of pituitary adenomas requires a balance of conservative management, surgical resection, and in select tumor types, molecular therapy. Acromegaly treatment is an evolving field where our understanding of molecular targets and drug therapies has improved treatment options for pa...

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Detalles Bibliográficos
Autores principales: Mooney, Michael A., Simon, Elias D., Little, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963385/
https://www.ncbi.nlm.nih.gov/pubmed/27517036
http://dx.doi.org/10.3389/fsurg.2016.00045
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author Mooney, Michael A.
Simon, Elias D.
Little, Andrew S.
author_facet Mooney, Michael A.
Simon, Elias D.
Little, Andrew S.
author_sort Mooney, Michael A.
collection PubMed
description The current treatment of pituitary adenomas requires a balance of conservative management, surgical resection, and in select tumor types, molecular therapy. Acromegaly treatment is an evolving field where our understanding of molecular targets and drug therapies has improved treatment options for patients with excess growth hormone levels. We highlight the use of molecular therapies in this disease process and advances in this field, which may represent a paradigm shift for the future of pituitary adenoma treatment.
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spelling pubmed-49633852016-08-11 Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms Mooney, Michael A. Simon, Elias D. Little, Andrew S. Front Surg Surgery The current treatment of pituitary adenomas requires a balance of conservative management, surgical resection, and in select tumor types, molecular therapy. Acromegaly treatment is an evolving field where our understanding of molecular targets and drug therapies has improved treatment options for patients with excess growth hormone levels. We highlight the use of molecular therapies in this disease process and advances in this field, which may represent a paradigm shift for the future of pituitary adenoma treatment. Frontiers Media S.A. 2016-07-28 /pmc/articles/PMC4963385/ /pubmed/27517036 http://dx.doi.org/10.3389/fsurg.2016.00045 Text en Copyright © 2016 Mooney, Simon and Little. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Mooney, Michael A.
Simon, Elias D.
Little, Andrew S.
Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms
title Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms
title_full Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms
title_fullStr Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms
title_full_unstemmed Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms
title_short Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms
title_sort advancing treatment of pituitary adenomas through targeted molecular therapies: the acromegaly and cushing disease paradigms
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963385/
https://www.ncbi.nlm.nih.gov/pubmed/27517036
http://dx.doi.org/10.3389/fsurg.2016.00045
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