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Inhibition of DNA Methylation Impairs Synaptic Plasticity during an Early Time Window in Rats

Although the importance of DNA methylation-dependent gene expression to neuronal plasticity is well established, the dynamics of methylation and demethylation during the induction and expression of synaptic plasticity have not been explored. Here, we combined electrophysiological, pharmacological, m...

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Detalles Bibliográficos
Autores principales: Muñoz, Pablo, Estay, Carolina, Díaz, Paula, Elgueta, Claudio, Ardiles, Álvaro O., Lizana, Pablo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963592/
https://www.ncbi.nlm.nih.gov/pubmed/27493805
http://dx.doi.org/10.1155/2016/4783836