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Modulating Dickkopf-1: A Strategy to Monitor or Treat Cancer?

Dickkopf-1 (DKK1) is a secreted Wnt/β-catenin pathway antagonist involved in embryogenesis. It was first described 25 years ago for its function in head induction and limb morphogenesis. Since then, this protein has been widely studied in the context of active Wnt/β-catenin signalling during cellula...

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Detalles Bibliográficos
Autores principales: Mazon, Mélody, Masi, Delphine, Carreau, Madeleine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963804/
https://www.ncbi.nlm.nih.gov/pubmed/27367730
http://dx.doi.org/10.3390/cancers8070062