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Hepatitis C virus infection among patients with diabetes mellitus in Dammam, Saudi Arabia
BACKGROUND: Data regarding comorbidities of hepatitis C virus infection (HCV) in the kingdom of Saudi Arabia (KSA) are lacking. The present study aimed to determine the prevalence and risk factors of HCV among Saudi patients with diabetes mellitus (DM) in Dammam, KSA. METHODS: In this cross-sectiona...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963943/ https://www.ncbi.nlm.nih.gov/pubmed/27464785 http://dx.doi.org/10.1186/s12913-016-1578-0 |
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author | Ba-Essa, Ebtesam M. Mobarak, Eman I. Al-Daghri, Nasser M. |
author_facet | Ba-Essa, Ebtesam M. Mobarak, Eman I. Al-Daghri, Nasser M. |
author_sort | Ba-Essa, Ebtesam M. |
collection | PubMed |
description | BACKGROUND: Data regarding comorbidities of hepatitis C virus infection (HCV) in the kingdom of Saudi Arabia (KSA) are lacking. The present study aimed to determine the prevalence and risk factors of HCV among Saudi patients with diabetes mellitus (DM) in Dammam, KSA. METHODS: In this cross-sectional study done in 2011, a total of 1054 Saudi DM patients were randomly selected from the Diabetes Center in Dammam Medical Complex, KSA, for interview and HCV screening using the HCV Rapid Test. Positive cases were later confirmed via INNO-LIA HCV score line immune assay. RESULTS: Seropositivity of HCV was 1.9 %. DM duration of >5 years increased the probability of HCV risk to 3.7 fold while insulin users were 3.2 times more likely to have HCV infection. Increased hospital admission (3–4 times) also increased HCV risk by 11.5 times and 13.6 times among patients with ≥5 admissions. Similarly, having 3–4 surgical procedures increased HCV risk by 8.6 times and 39.3 times with ≥5 procedures. HCV transmission is 4 times more likely by blood transfusion. Those who shared personal items were 8.5 times more likely to have HCV. Tattooing increased HCV risk by 6.7 times. The likelihood of HCV infection was also higher among DM patients with liver diseases and elevated liver enzymes. CONCLUSION: The study confirmed a significant association between HCV risk and DM. Frequency of HCV among DM Saudis was 1.9 %. Predictors of HCV among DM patients were sharing personal items, occupational exposure to blood or its products, elevated transaminases, tattooing, disease duration > 5 years, increased hospital admission and blood transfusion. |
format | Online Article Text |
id | pubmed-4963943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-49639432016-07-29 Hepatitis C virus infection among patients with diabetes mellitus in Dammam, Saudi Arabia Ba-Essa, Ebtesam M. Mobarak, Eman I. Al-Daghri, Nasser M. BMC Health Serv Res Research Article BACKGROUND: Data regarding comorbidities of hepatitis C virus infection (HCV) in the kingdom of Saudi Arabia (KSA) are lacking. The present study aimed to determine the prevalence and risk factors of HCV among Saudi patients with diabetes mellitus (DM) in Dammam, KSA. METHODS: In this cross-sectional study done in 2011, a total of 1054 Saudi DM patients were randomly selected from the Diabetes Center in Dammam Medical Complex, KSA, for interview and HCV screening using the HCV Rapid Test. Positive cases were later confirmed via INNO-LIA HCV score line immune assay. RESULTS: Seropositivity of HCV was 1.9 %. DM duration of >5 years increased the probability of HCV risk to 3.7 fold while insulin users were 3.2 times more likely to have HCV infection. Increased hospital admission (3–4 times) also increased HCV risk by 11.5 times and 13.6 times among patients with ≥5 admissions. Similarly, having 3–4 surgical procedures increased HCV risk by 8.6 times and 39.3 times with ≥5 procedures. HCV transmission is 4 times more likely by blood transfusion. Those who shared personal items were 8.5 times more likely to have HCV. Tattooing increased HCV risk by 6.7 times. The likelihood of HCV infection was also higher among DM patients with liver diseases and elevated liver enzymes. CONCLUSION: The study confirmed a significant association between HCV risk and DM. Frequency of HCV among DM Saudis was 1.9 %. Predictors of HCV among DM patients were sharing personal items, occupational exposure to blood or its products, elevated transaminases, tattooing, disease duration > 5 years, increased hospital admission and blood transfusion. BioMed Central 2016-07-27 /pmc/articles/PMC4963943/ /pubmed/27464785 http://dx.doi.org/10.1186/s12913-016-1578-0 Text en © Ba-Essa et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Ba-Essa, Ebtesam M. Mobarak, Eman I. Al-Daghri, Nasser M. Hepatitis C virus infection among patients with diabetes mellitus in Dammam, Saudi Arabia |
title | Hepatitis C virus infection among patients with diabetes mellitus in Dammam, Saudi Arabia |
title_full | Hepatitis C virus infection among patients with diabetes mellitus in Dammam, Saudi Arabia |
title_fullStr | Hepatitis C virus infection among patients with diabetes mellitus in Dammam, Saudi Arabia |
title_full_unstemmed | Hepatitis C virus infection among patients with diabetes mellitus in Dammam, Saudi Arabia |
title_short | Hepatitis C virus infection among patients with diabetes mellitus in Dammam, Saudi Arabia |
title_sort | hepatitis c virus infection among patients with diabetes mellitus in dammam, saudi arabia |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963943/ https://www.ncbi.nlm.nih.gov/pubmed/27464785 http://dx.doi.org/10.1186/s12913-016-1578-0 |
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