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Post-burn breast reconstruction using an artificial dermis—a long-term follow-up

BACKGROUND: Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options. Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen. The dermal matrix serves as a scaffold for fibroblasts and end...

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Detalles Bibliográficos
Autores principales: Gronovich, Yoav, Maisel Lotan, Adi, Retchkiman, Meir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964029/
https://www.ncbi.nlm.nih.gov/pubmed/27574682
http://dx.doi.org/10.1186/s41038-016-0037-9
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author Gronovich, Yoav
Maisel Lotan, Adi
Retchkiman, Meir
author_facet Gronovich, Yoav
Maisel Lotan, Adi
Retchkiman, Meir
author_sort Gronovich, Yoav
collection PubMed
description BACKGROUND: Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options. Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen. The dermal matrix serves as a scaffold for fibroblasts and endothelial cells. Vascularization of the matrix begins after 2–3 weeks, and eventually, the matrix incorporates with the tissue to create a new dermis. The main advantage of the Integra is that the neodermis is of the same quality as a native dermis. CASE PRESENTATION: In this case report, we present post-burn breast reconstruction of a 12-year-old girl using Integra, with a long follow-up of 7 years. To the best of our knowledge, there is no published follow-up of breast development after reconstruction with Integra from its beginning point at the age of puberty until after the growing process has terminated. CONCLUSIONS: Integra is a reliable reconstructive tool for burned breast. If done before puberty, it can help in getting normal developing tissue with satisfying esthetic results of size, shape and symmetry.
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spelling pubmed-49640292016-08-29 Post-burn breast reconstruction using an artificial dermis—a long-term follow-up Gronovich, Yoav Maisel Lotan, Adi Retchkiman, Meir Burns Trauma Case Report BACKGROUND: Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options. Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen. The dermal matrix serves as a scaffold for fibroblasts and endothelial cells. Vascularization of the matrix begins after 2–3 weeks, and eventually, the matrix incorporates with the tissue to create a new dermis. The main advantage of the Integra is that the neodermis is of the same quality as a native dermis. CASE PRESENTATION: In this case report, we present post-burn breast reconstruction of a 12-year-old girl using Integra, with a long follow-up of 7 years. To the best of our knowledge, there is no published follow-up of breast development after reconstruction with Integra from its beginning point at the age of puberty until after the growing process has terminated. CONCLUSIONS: Integra is a reliable reconstructive tool for burned breast. If done before puberty, it can help in getting normal developing tissue with satisfying esthetic results of size, shape and symmetry. BioMed Central 2016-07-04 /pmc/articles/PMC4964029/ /pubmed/27574682 http://dx.doi.org/10.1186/s41038-016-0037-9 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Gronovich, Yoav
Maisel Lotan, Adi
Retchkiman, Meir
Post-burn breast reconstruction using an artificial dermis—a long-term follow-up
title Post-burn breast reconstruction using an artificial dermis—a long-term follow-up
title_full Post-burn breast reconstruction using an artificial dermis—a long-term follow-up
title_fullStr Post-burn breast reconstruction using an artificial dermis—a long-term follow-up
title_full_unstemmed Post-burn breast reconstruction using an artificial dermis—a long-term follow-up
title_short Post-burn breast reconstruction using an artificial dermis—a long-term follow-up
title_sort post-burn breast reconstruction using an artificial dermis—a long-term follow-up
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964029/
https://www.ncbi.nlm.nih.gov/pubmed/27574682
http://dx.doi.org/10.1186/s41038-016-0037-9
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