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Post-burn breast reconstruction using an artificial dermis—a long-term follow-up
BACKGROUND: Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options. Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen. The dermal matrix serves as a scaffold for fibroblasts and end...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964029/ https://www.ncbi.nlm.nih.gov/pubmed/27574682 http://dx.doi.org/10.1186/s41038-016-0037-9 |
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author | Gronovich, Yoav Maisel Lotan, Adi Retchkiman, Meir |
author_facet | Gronovich, Yoav Maisel Lotan, Adi Retchkiman, Meir |
author_sort | Gronovich, Yoav |
collection | PubMed |
description | BACKGROUND: Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options. Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen. The dermal matrix serves as a scaffold for fibroblasts and endothelial cells. Vascularization of the matrix begins after 2–3 weeks, and eventually, the matrix incorporates with the tissue to create a new dermis. The main advantage of the Integra is that the neodermis is of the same quality as a native dermis. CASE PRESENTATION: In this case report, we present post-burn breast reconstruction of a 12-year-old girl using Integra, with a long follow-up of 7 years. To the best of our knowledge, there is no published follow-up of breast development after reconstruction with Integra from its beginning point at the age of puberty until after the growing process has terminated. CONCLUSIONS: Integra is a reliable reconstructive tool for burned breast. If done before puberty, it can help in getting normal developing tissue with satisfying esthetic results of size, shape and symmetry. |
format | Online Article Text |
id | pubmed-4964029 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-49640292016-08-29 Post-burn breast reconstruction using an artificial dermis—a long-term follow-up Gronovich, Yoav Maisel Lotan, Adi Retchkiman, Meir Burns Trauma Case Report BACKGROUND: Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options. Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen. The dermal matrix serves as a scaffold for fibroblasts and endothelial cells. Vascularization of the matrix begins after 2–3 weeks, and eventually, the matrix incorporates with the tissue to create a new dermis. The main advantage of the Integra is that the neodermis is of the same quality as a native dermis. CASE PRESENTATION: In this case report, we present post-burn breast reconstruction of a 12-year-old girl using Integra, with a long follow-up of 7 years. To the best of our knowledge, there is no published follow-up of breast development after reconstruction with Integra from its beginning point at the age of puberty until after the growing process has terminated. CONCLUSIONS: Integra is a reliable reconstructive tool for burned breast. If done before puberty, it can help in getting normal developing tissue with satisfying esthetic results of size, shape and symmetry. BioMed Central 2016-07-04 /pmc/articles/PMC4964029/ /pubmed/27574682 http://dx.doi.org/10.1186/s41038-016-0037-9 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Gronovich, Yoav Maisel Lotan, Adi Retchkiman, Meir Post-burn breast reconstruction using an artificial dermis—a long-term follow-up |
title | Post-burn breast reconstruction using an artificial dermis—a long-term follow-up |
title_full | Post-burn breast reconstruction using an artificial dermis—a long-term follow-up |
title_fullStr | Post-burn breast reconstruction using an artificial dermis—a long-term follow-up |
title_full_unstemmed | Post-burn breast reconstruction using an artificial dermis—a long-term follow-up |
title_short | Post-burn breast reconstruction using an artificial dermis—a long-term follow-up |
title_sort | post-burn breast reconstruction using an artificial dermis—a long-term follow-up |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964029/ https://www.ncbi.nlm.nih.gov/pubmed/27574682 http://dx.doi.org/10.1186/s41038-016-0037-9 |
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