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Short telomere length and its correlation with gene mutations in myelodysplastic syndrome

BACKGROUND: Telomere erosion can lead to genomic instability and cancer progression. It has been suggested that the shortest telomere, not the average telomere length (TL), is critical for cell viability. Some studies have shown shorter TL in myelodysplastic syndrome (MDS) patients but the criticall...

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Detalles Bibliográficos
Autores principales: Hwang, Sang Mee, Kim, Seon Young, Kim, Jung Ah, Park, Hee-Sue, Park, Si Nae, Im, Kyongok, Kim, Kwantae, Kim, Sung-Min, Lee, Dong Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964031/
https://www.ncbi.nlm.nih.gov/pubmed/27465399
http://dx.doi.org/10.1186/s13045-016-0287-9