Tissue engineering in burn scar reconstruction

Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions....

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Autores principales: van Zuijlen, PPM, Gardien, KLM, Jaspers, MEH, Bos, EJ, Baas, DC, van Trier, AJM, Middelkoop, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964040/
https://www.ncbi.nlm.nih.gov/pubmed/27574664
http://dx.doi.org/10.1186/s41038-015-0017-5
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author van Zuijlen, PPM
Gardien, KLM
Jaspers, MEH
Bos, EJ
Baas, DC
van Trier, AJM
Middelkoop, E
author_facet van Zuijlen, PPM
Gardien, KLM
Jaspers, MEH
Bos, EJ
Baas, DC
van Trier, AJM
Middelkoop, E
author_sort van Zuijlen, PPM
collection PubMed
description Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions. This review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery, focusing on usage and clinical effectiveness. Not only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage.
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spelling pubmed-49640402016-08-29 Tissue engineering in burn scar reconstruction van Zuijlen, PPM Gardien, KLM Jaspers, MEH Bos, EJ Baas, DC van Trier, AJM Middelkoop, E Burns Trauma Review Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions. This review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery, focusing on usage and clinical effectiveness. Not only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage. BioMed Central 2015-09-30 /pmc/articles/PMC4964040/ /pubmed/27574664 http://dx.doi.org/10.1186/s41038-015-0017-5 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
van Zuijlen, PPM
Gardien, KLM
Jaspers, MEH
Bos, EJ
Baas, DC
van Trier, AJM
Middelkoop, E
Tissue engineering in burn scar reconstruction
title Tissue engineering in burn scar reconstruction
title_full Tissue engineering in burn scar reconstruction
title_fullStr Tissue engineering in burn scar reconstruction
title_full_unstemmed Tissue engineering in burn scar reconstruction
title_short Tissue engineering in burn scar reconstruction
title_sort tissue engineering in burn scar reconstruction
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964040/
https://www.ncbi.nlm.nih.gov/pubmed/27574664
http://dx.doi.org/10.1186/s41038-015-0017-5
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