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Neurosyphilis as a great imitator: a case report
BACKGROUND: Neurosyphilis is defined as any involvement of the central nervous system by the bacterium Treponema pallidum. Movement disorders as manifestations of syphilis have been reported quite rarely. CASE PRESENTATION: We report a case of a 42-year-old Russian man living in Estonia with rapidly...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964046/ https://www.ncbi.nlm.nih.gov/pubmed/27465246 http://dx.doi.org/10.1186/s13104-016-2176-2 |
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author | Sabre, Liis Braschinsky, Mark Taba, Pille |
author_facet | Sabre, Liis Braschinsky, Mark Taba, Pille |
author_sort | Sabre, Liis |
collection | PubMed |
description | BACKGROUND: Neurosyphilis is defined as any involvement of the central nervous system by the bacterium Treponema pallidum. Movement disorders as manifestations of syphilis have been reported quite rarely. CASE PRESENTATION: We report a case of a 42-year-old Russian man living in Estonia with rapidly progressive dementia and movement disorders manifesting as myoclonus, cerebellar ataxia and parkinsonism. The mini mental state examination score was 12/30. After excluding different neurodegenerative causes, further diagnostic testing was consistent with neurosyphilis. Treatment with penicillin was started and 6 months later his mini mental state examination score was 25/30 and he had no myoclonus, parkinsonism or cerebellar dysfunction. CONCLUSION: Since syphilis is easily diagnosed and treatable, it should be considered and tested in patients with cognitive impairment and movement disorders. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13104-016-2176-2) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4964046 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-49640462016-07-29 Neurosyphilis as a great imitator: a case report Sabre, Liis Braschinsky, Mark Taba, Pille BMC Res Notes Case Report BACKGROUND: Neurosyphilis is defined as any involvement of the central nervous system by the bacterium Treponema pallidum. Movement disorders as manifestations of syphilis have been reported quite rarely. CASE PRESENTATION: We report a case of a 42-year-old Russian man living in Estonia with rapidly progressive dementia and movement disorders manifesting as myoclonus, cerebellar ataxia and parkinsonism. The mini mental state examination score was 12/30. After excluding different neurodegenerative causes, further diagnostic testing was consistent with neurosyphilis. Treatment with penicillin was started and 6 months later his mini mental state examination score was 25/30 and he had no myoclonus, parkinsonism or cerebellar dysfunction. CONCLUSION: Since syphilis is easily diagnosed and treatable, it should be considered and tested in patients with cognitive impairment and movement disorders. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13104-016-2176-2) contains supplementary material, which is available to authorized users. BioMed Central 2016-07-28 /pmc/articles/PMC4964046/ /pubmed/27465246 http://dx.doi.org/10.1186/s13104-016-2176-2 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Sabre, Liis Braschinsky, Mark Taba, Pille Neurosyphilis as a great imitator: a case report |
title | Neurosyphilis as a great imitator: a case report |
title_full | Neurosyphilis as a great imitator: a case report |
title_fullStr | Neurosyphilis as a great imitator: a case report |
title_full_unstemmed | Neurosyphilis as a great imitator: a case report |
title_short | Neurosyphilis as a great imitator: a case report |
title_sort | neurosyphilis as a great imitator: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964046/ https://www.ncbi.nlm.nih.gov/pubmed/27465246 http://dx.doi.org/10.1186/s13104-016-2176-2 |
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