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High EZH2 expression is correlated to metastatic disease in pediatric soft tissue sarcomas

BACKGROUND: Enhancer of Zeste Drosophila Homologue 2 (EZH2) is a key regulator of transcription as a member of polycomb repressive complex 2 (PRC2) which exerts repression of downstream genes and is correlated to invasiveness and progression of different tumours. Therefore, we evaluated the expressi...

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Detalles Bibliográficos
Autores principales:	Ramaglia, Maria, D’Angelo, Velia, Iannotta, Adriana, Di Pinto, Daniela, Pota, Elvira, Affinita, Maria Carmen, Donofrio, Vittoria, Errico, Maria Elena, Lombardi, Angela, Indolfi, Cristiana, Casale, Fiorina, Caraglia, Michele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964052/ https://www.ncbi.nlm.nih.gov/pubmed/27471434 http://dx.doi.org/10.1186/s12935-016-0338-x

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