A phase I, placebo-controlled, randomized, double-blind, single ascending dose-ranging study to evaluate the safety and tolerability of a novel biophysical bronchodilator (S-1226) administered by nebulization in healthy volunteers

BACKGROUND: A major challenge in treating acute asthma exacerbations is the need to open constricted airways rapidly enough to reestablish ventilation and allow delivery of conventional medication to diseased airways. The solution requires a new approach that considers both biophysical and pharmacol...

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Detalles Bibliográficos
Autores principales: Green, Francis H. Y., Leigh, Richard, Fadayomi, Morenike, Lalli, Gurkeet, Chiu, Andrea, Shrestha, Grishma, ElShahat, Sharif G., Nelson, David Evan, El Mays, Tamer Y., Pieron, Cora A., Dennis, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964056/
https://www.ncbi.nlm.nih.gov/pubmed/27464582
http://dx.doi.org/10.1186/s13063-016-1489-8

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