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Simulation study to determine the impact of different design features on design efficiency in discrete choice experiments

OBJECTIVES: Discrete choice experiments (DCEs) are routinely used to elicit patient preferences to improve health outcomes and healthcare services. While many fractional factorial designs can be created, some are more statistically optimal than others. The objective of this simulation study was to i...

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Autores principales: Vanniyasingam, Thuva, Cunningham, Charles E, Foster, Gary, Thabane, Lehana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964187/
https://www.ncbi.nlm.nih.gov/pubmed/27436671
http://dx.doi.org/10.1136/bmjopen-2016-011985
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author Vanniyasingam, Thuva
Cunningham, Charles E
Foster, Gary
Thabane, Lehana
author_facet Vanniyasingam, Thuva
Cunningham, Charles E
Foster, Gary
Thabane, Lehana
author_sort Vanniyasingam, Thuva
collection PubMed
description OBJECTIVES: Discrete choice experiments (DCEs) are routinely used to elicit patient preferences to improve health outcomes and healthcare services. While many fractional factorial designs can be created, some are more statistically optimal than others. The objective of this simulation study was to investigate how varying the number of (1) attributes, (2) levels within attributes, (3) alternatives and (4) choice tasks per survey will improve or compromise the statistical efficiency of an experimental design. DESIGN AND METHODS: A total of 3204 DCE designs were created to assess how relative design efficiency (d-efficiency) is influenced by varying the number of choice tasks (2–20), alternatives (2–5), attributes (2–20) and attribute levels (2–5) of a design. Choice tasks were created by randomly allocating attribute and attribute level combinations into alternatives. OUTCOME: Relative d-efficiency was used to measure the optimality of each DCE design. RESULTS: DCE design complexity influenced statistical efficiency. Across all designs, relative d-efficiency decreased as the number of attributes and attribute levels increased. It increased for designs with more alternatives. Lastly, relative d-efficiency converges as the number of choice tasks increases, where convergence may not be at 100% statistical optimality. CONCLUSIONS: Achieving 100% d-efficiency is heavily dependent on the number of attributes, attribute levels, choice tasks and alternatives. Further exploration of overlaps and block sizes are needed. This study's results are widely applicable for researchers interested in creating optimal DCE designs to elicit individual preferences on health services, programmes, policies and products.
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spelling pubmed-49641872016-08-03 Simulation study to determine the impact of different design features on design efficiency in discrete choice experiments Vanniyasingam, Thuva Cunningham, Charles E Foster, Gary Thabane, Lehana BMJ Open Research Methods OBJECTIVES: Discrete choice experiments (DCEs) are routinely used to elicit patient preferences to improve health outcomes and healthcare services. While many fractional factorial designs can be created, some are more statistically optimal than others. The objective of this simulation study was to investigate how varying the number of (1) attributes, (2) levels within attributes, (3) alternatives and (4) choice tasks per survey will improve or compromise the statistical efficiency of an experimental design. DESIGN AND METHODS: A total of 3204 DCE designs were created to assess how relative design efficiency (d-efficiency) is influenced by varying the number of choice tasks (2–20), alternatives (2–5), attributes (2–20) and attribute levels (2–5) of a design. Choice tasks were created by randomly allocating attribute and attribute level combinations into alternatives. OUTCOME: Relative d-efficiency was used to measure the optimality of each DCE design. RESULTS: DCE design complexity influenced statistical efficiency. Across all designs, relative d-efficiency decreased as the number of attributes and attribute levels increased. It increased for designs with more alternatives. Lastly, relative d-efficiency converges as the number of choice tasks increases, where convergence may not be at 100% statistical optimality. CONCLUSIONS: Achieving 100% d-efficiency is heavily dependent on the number of attributes, attribute levels, choice tasks and alternatives. Further exploration of overlaps and block sizes are needed. This study's results are widely applicable for researchers interested in creating optimal DCE designs to elicit individual preferences on health services, programmes, policies and products. BMJ Publishing Group 2016-07-19 /pmc/articles/PMC4964187/ /pubmed/27436671 http://dx.doi.org/10.1136/bmjopen-2016-011985 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Research Methods
Vanniyasingam, Thuva
Cunningham, Charles E
Foster, Gary
Thabane, Lehana
Simulation study to determine the impact of different design features on design efficiency in discrete choice experiments
title Simulation study to determine the impact of different design features on design efficiency in discrete choice experiments
title_full Simulation study to determine the impact of different design features on design efficiency in discrete choice experiments
title_fullStr Simulation study to determine the impact of different design features on design efficiency in discrete choice experiments
title_full_unstemmed Simulation study to determine the impact of different design features on design efficiency in discrete choice experiments
title_short Simulation study to determine the impact of different design features on design efficiency in discrete choice experiments
title_sort simulation study to determine the impact of different design features on design efficiency in discrete choice experiments
topic Research Methods
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964187/
https://www.ncbi.nlm.nih.gov/pubmed/27436671
http://dx.doi.org/10.1136/bmjopen-2016-011985
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