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PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells

BACKGROUND: Triple-negative breast cancer (TNBC) is an aggressive histological subtype with limited treatment options and very poor prognosis following progression after standard chemotherapeutic regimens. Therefore, novel molecules and therapeutic options are urgently needed for this category of pa...

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Detalles Bibliográficos
Autores principales: Al-Howail, Huda A., Hakami, Hana A., Al-Otaibi, Basem, Al-Mazrou, Amer, Daghestani, Maha H., Al-Jammaz, Ibrahim, Al-Khalaf, Huda H., Aboussekhra, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964287/
https://www.ncbi.nlm.nih.gov/pubmed/27465411
http://dx.doi.org/10.1186/s12885-016-2583-8