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PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells
BACKGROUND: Triple-negative breast cancer (TNBC) is an aggressive histological subtype with limited treatment options and very poor prognosis following progression after standard chemotherapeutic regimens. Therefore, novel molecules and therapeutic options are urgently needed for this category of pa...
Autores principales: | Al-Howail, Huda A., Hakami, Hana A., Al-Otaibi, Basem, Al-Mazrou, Amer, Daghestani, Maha H., Al-Jammaz, Ibrahim, Al-Khalaf, Huda H., Aboussekhra, Abdelilah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964287/ https://www.ncbi.nlm.nih.gov/pubmed/27465411 http://dx.doi.org/10.1186/s12885-016-2583-8 |
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