Poly(ADP-ribose) polymerase inhibition suppresses inflammation and promotes recovery from adrenal injury in a rat model of acute necrotizing pancreatitis

BACKGROUND: Poly(ADP-ribose) polymerase (PARP) participates in multi-organ failure in various inflammatory diseases including acute necrotizing pancreatitis (ANP). Since pancreatitis-associated adrenal insufficiency is partly caused by inflammatory damage to the adrenal cortex, we examined whether P...

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Detalles Bibliográficos
Autores principales: Yu, Jia, Zuo, Teng, Deng, Wenhong, Shi, Qiao, Ma, Peng, Chen, Chen, Zhao, Liang, Zhao, Kailiang, Wang, Weixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964309/
https://www.ncbi.nlm.nih.gov/pubmed/27465581
http://dx.doi.org/10.1186/s12876-016-0493-5

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