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ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS

The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening...

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Detalles Bibliográficos
Autores principales: BAEZ, Camila Freze, SAVASSI-RIBAS, Flavia, da ROCHA, Wilker Menezes, ALMEIDA, Stéphanie G. S., GONÇALVES, Marianna T. V., GUIMARÃES, Maria Angelica A. M., CAVALCANTI, Silvia Maria B., VARELLA, Rafael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964327/
https://www.ncbi.nlm.nih.gov/pubmed/27410918
http://dx.doi.org/10.1590/S1678-9946201658058
Descripción
Sumario:The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening by PCR for both viruses. According to the results, EBV was strongly associated with gingivitis and/or periodontitis in transplanted individuals (p = 0.011) but not HPV (p = 0.766). EBV-HPV co-detections did not enhance the presence of tissue injury as well. Although a causal relationship was not investigated in this study, the higher frequency of these two oncoviruses in lesion tissues must be investigated in follow-up studies, especially among immunocompromised individuals.