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Computational Identification of the Paralogs and Orthologs of Human Cytochrome P450 Superfamily and the Implication in Drug Discovery

The human cytochrome P450 (CYP) superfamily consisting of 57 functional genes is the most important group of Phase I drug metabolizing enzymes that oxidize a large number of xenobiotics and endogenous compounds, including therapeutic drugs and environmental toxicants. The CYP superfamily has been sh...

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Detalles Bibliográficos
Autores principales:	Pan, Shu-Ting, Xue, Danfeng, Li, Zhi-Ling, Zhou, Zhi-Wei, He, Zhi-Xu, Yang, Yinxue, Yang, Tianxin, Qiu, Jia-Xuan, Zhou, Shu-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964396/ https://www.ncbi.nlm.nih.gov/pubmed/27367670 http://dx.doi.org/10.3390/ijms17071020

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