Cargando…

Novel NSAID-Derived Drugs for the Potential Treatment of Alzheimer’s Disease

Nonsteroidal anti-inflammatory drugs (NSAIDs) have been suggested for the potential treatment of neurodegenerative diseases, such as Alzheimer’s disease (AD). Prolonged use of NSAIDs, however, produces gastrointestinal (GI) toxicity. To overcome this serious limitation, the aim of this study was to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cacciatore, Ivana, Marinelli, Lisa, Fornasari, Erika, Cerasa, Laura S., Eusepi, Piera, Türkez, Hasan, Pomilio, Cristina, Reale, Marcella, D’Angelo, Chiara, Costantini, Erica, Di Stefano, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964411/ https://www.ncbi.nlm.nih.gov/pubmed/27376271 http://dx.doi.org/10.3390/ijms17071035

Ejemplares similares

Histidyl-Proline Diketopiperazine Isomers as Multipotent Anti-Alzheimer Drug Candidates
por: Turkez, Hasan, et al.
Publicado: (2020)

Carvacrol Codrugs: A New Approach in the Antimicrobial Plan
por: Cacciatore, Ivana, et al.
Publicado: (2015)

In Vitro Wound-Healing Properties of Water-Soluble Terpenoids Loaded on Halloysite Clay
por: Marinelli, Lisa, et al.
Publicado: (2021)

Glycyl-L-Prolyl-L-Glutamate Pseudotripeptides for Treatment of Alzheimer’s Disease
por: Turkez, Hasan, et al.
Publicado: (2021)

Carvacrol Prodrugs with Antimicrobial Activity Loaded on Clay Nanocomposites
por: Eusepi, Piera, et al.
Publicado: (2020)

Wound-Healing Promotion and Anti-Inflammatory Properties of Carvacrol Prodrugs/Hyaluronic Acid Formulations
por: Marinelli, Lisa, et al.
Publicado: (2022)

Transdermal donepezil on the treatment of Alzheimer’s disease
por: Sozio, Piera, et al.
Publicado: (2012)

The Role of Immunosenescence in Neurodegenerative Diseases
por: Costantini, Erica, et al.
Publicado: (2018)

Microbiota and Probiotics in Health and HIV Infection
por: D’Angelo, Chiara, et al.
Publicado: (2017)

Synthesis and Biological Evaluation of Novel Selenyl and Sulfur-l-Dopa Derivatives as Potential Anti-Parkinson’s Disease Agents
por: Di Stefano, Antonio, et al.
Publicado: (2019)

New Flurbiprofen Derivatives: Synthesis, Membrane Affinity and Evaluation of in Vitro Effect on β-Amyloid Levels
por: Sozio, Piera, et al.
Publicado: (2013)

Boron Nitride Nanoparticles Loaded with a Boron-Based Hybrid as a Promising Drug Carrier System for Alzheimer’s Disease Treatment
por: Yıldırım, Özge Çağlar, et al.
Publicado: (2022)

Relationship of Wine Consumption with Alzheimer’s Disease
por: Reale, Marcella, et al.
Publicado: (2020)

Human Gingival Fibroblasts Exposed to Extremely Low-Frequency Electromagnetic Fields: In Vitro Model of Wound-Healing Improvement
por: Costantini, Erica, et al.
Publicado: (2019)

Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-β Deposition in the APP(SWE)/PS1dE9 Mouse Model of Alzheimer’s Disease Pathology
por: Reale, Marcella, et al.
Publicado: (2018)

Novel styryl-thiazole hybrids as potential anti-Alzheimer's agents
por: Gouleni, Niki, et al.
Publicado: (2023)

Management of Osteoarthritis: Expert Opinion on NSAIDs
por: Magni, Alberto, et al.
Publicado: (2021)

Toxicity of Glycyl-l-Prolyl-l-Glutamate Pseudotripeptides: Cytotoxic, Oxidative, Genotoxic, and Embryotoxic Perspectives
por: Turkez, Hasan, et al.
Publicado: (2022)

Recent Advances in the Treatment of Neurodegenerative Diseases Based on GSH Delivery Systems
por: Cacciatore, Ivana, et al.
Publicado: (2012)

Neuronal Cellular Responses to Extremely Low Frequency Electromagnetic Field Exposure: Implications Regarding Oxidative Stress and Neurodegeneration
por: Reale, Marcella, et al.
Publicado: (2014)

Publisher Correction: nAChRs gene expression and neuroinflammation in APPswe/PS1dE9 transgenic mouse
por: D’Angelo, Chiara, et al.
Publicado: (2021)

nAChRs gene expression and neuroinflammation in APPswe/PS1dE9 transgenic mouse
por: D’Angelo, Chiara, et al.
Publicado: (2021)

Cholinergic Markers and Cytokines in OSA Patients
por: Reale, Marcella, et al.
Publicado: (2020)

Anti-Obesity and Anti-Inflammatory Effects of Novel Carvacrol Derivatives on 3T3-L1 and WJ-MSCs Cells
por: Cacciatore, Ivana, et al.
Publicado: (2023)

Network between Cytokines, Cortisol and Occupational Stress in Gas and Oilfield Workers
por: Reale, Marcella, et al.
Publicado: (2020)

NSAIDs-dependent adaption of the mitochondria-proteasome system in immortalized human cardiomyocytes
por: Brandolini, Laura, et al.
Publicado: (2020)

Role of Dietary Supplements in the Management of Parkinson’s Disease
por: Ciulla, Michele, et al.
Publicado: (2019)

Cholinergic Modulation of the Immune System in Neuroinflammatory Diseases
por: Reale, Marcella, et al.
Publicado: (2021)

NSAIDs: How they Work and their Prospects as Therapeutics in Alzheimer's Disease
por: Sastre, Magdalena, et al.
Publicado: (2010)

Healthcare Systems across Europe and the US: The Managed Entry Agreements Experience
por: Ciulla, Michele, et al.
Publicado: (2023)

Profiling of Canonical and Non-Traditional Cytokine Levels in Interferon-β-Treated Relapsing–Remitting-Multiple Sclerosis Patients
por: D’Angelo, Chiara, et al.
Publicado: (2018)

Dysregulated Homeostasis of Acetylcholine Levels in Immune Cells of RR-Multiple Sclerosis Patients
por: Di Bari, Maria, et al.
Publicado: (2016)

Are NSAIDs Useful to Treat Alzheimer's Disease or Mild Cognitive Impairment?
por: Imbimbo, Bruno P., et al.
Publicado: (2010)

A Potent (R)-alpha-bis-lipoyl Derivative Containing 8-Hydroxyquinoline Scaffold: Synthesis and Biological Evaluation of Its Neuroprotective Capabilities in SH-SY5Y Human Neuroblastoma Cells
por: Cacciatore, Ivana, et al.
Publicado: (2013)

P003. NSAIDs for symptomatic treatment of headache
por: Affaitati, Giannapia, et al.
Publicado: (2015)

Ameliorative Effects by Hexagonal Boron Nitride Nanoparticles against Beta Amyloid Induced Neurotoxicity
por: Aydin, Nursah, et al.
Publicado: (2022)

Cytokine Imbalance in Schizophrenia. From Research to Clinic: Potential Implications for Treatment
por: Reale, Marcella, et al.
Publicado: (2021)

A Novel Prodrug of a nNOS Inhibitor with Improved Pharmacokinetic Potential
por: Maccallini, Cristina, et al.
Publicado: (2020)

Caution with NSAIDs
por: Crighton, A., et al.
Publicado: (2020)

Wound Repair and Extremely Low Frequency-Electromagnetic Field: Insight from In Vitro Study and Potential Clinical Application
por: Gualdi, Giulio, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j83h24s3rhtc1mbu4oibugrr2t