Cargando…

Analysis of the Interaction of Dp44mT with Human Serum Albumin and Calf Thymus DNA Using Molecular Docking and Spectroscopic Techniques

Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone (Dp44mT) exhibits significant antitumor activity. However, the mechanism of its pharmacological interaction with human serum albumin (HSA) and DNA remains poorly understood. Here, we aimed to elucidate the interactions of Dp44mT with HSA and DNA u...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Zhongjie, Liu, Youxun, Zhou, Sufeng, Fu, Yun, Li, Changzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964418/
https://www.ncbi.nlm.nih.gov/pubmed/27376275
http://dx.doi.org/10.3390/ijms17071042

Ejemplares similares