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Molecular Targeted Therapies for the Treatment of Leptomeningeal Carcinomatosis: Current Evidence and Future Directions

Leptomeningeal carcinomatosis (LMC) is the multifocal seeding of cerebrospinal fluid and leptomeninges by malignant cells. The incidence of LMC is approximately 5% in patients with malignant tumors overall and the rate is increasing due to increasing survival time of cancer patients. Eradication of...

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Detalles Bibliográficos
Autores principales: Lee, Dae-Won, Lee, Kyung-Hun, Kim, Jin Wook, Keam, Bhumsuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964450/
https://www.ncbi.nlm.nih.gov/pubmed/27399673
http://dx.doi.org/10.3390/ijms17071074