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Exploring the Molecular Basis for Binding of Inhibitors by Threonyl-tRNA Synthetase from Brucella abortus: A Virtual Screening Study

Targeting threonyl-tRNA synthetase (ThrRS) of Brucella abortus is a promising approach to developing small-molecule drugs against bovine brucellosis. Using the BLASTp algorithm, we identified ThrRS from Escherichia coli (EThrRS, PDB ID 1QF6), which is 51% identical to ThrRS from Brucella abortus (Ba...

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Detalles Bibliográficos
Autores principales:	Li, Ming, Wen, Fang, Zhao, Shengguo, Wang, Pengpeng, Li, Songli, Zhang, Yangdong, Zheng, Nan, Wang, Jiaqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964454/ https://www.ncbi.nlm.nih.gov/pubmed/27447614 http://dx.doi.org/10.3390/ijms17071078

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