Synthesis and Evaluation of Tricarbonyl (99m)Tc-Labeled 2-(4-Chloro)phenyl-imidazo[1,2-a]pyridine Analogs as Novel SPECT Imaging Radiotracer for TSPO-Rich Cancer

The 18-kDa translocator protein (TSPO) levels are associated with brain, breast, and prostate cancer progression and have emerged as viable targets for cancer therapy and imaging. In order to develop highly selective and active ligands with a high affinity for TSPO, imidazopyridine-based TSPO ligand...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Ji Young, Iacobazzi, Rosa Maria, Perrone, Mara, Margiotta, Nicola, Cutrignelli, Annalisa, Jung, Jae Ho, Park, Do Dam, Moon, Byung Seok, Denora, Nunzio, Kim, Sang Eun, Lee, Byung Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964461/
https://www.ncbi.nlm.nih.gov/pubmed/27399688
http://dx.doi.org/10.3390/ijms17071085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964461/
https://www.ncbi.nlm.nih.gov/pubmed/27399688
http://dx.doi.org/10.3390/ijms17071085

Ejemplares similares