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Allelic Variation of the Capsule Promoter Diversifies Encapsulation and Virulence In Streptococcus pneumoniae
The polysaccharide capsule is the major virulence factor of Streptococcus pneumoniae (pneumococcus), a major human pathogen. The sequences in the promoter and coding regions of the capsule gene locus undergo extensive variations through the natural transformation-mediated horizontal gene transfer. T...
Autores principales: | Wen, Zhensong, Liu, Yanni, Qu, Fen, Zhang, Jing-Ren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964562/ https://www.ncbi.nlm.nih.gov/pubmed/27465908 http://dx.doi.org/10.1038/srep30176 |
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