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Allele-specific locus binding and genome editing by CRISPR at the p16INK4a locus
The clustered regularly interspaced short palindromic repeats (CRISPR) system has been adopted for a wide range of biological applications including genome editing. In some cases, dissection of genome functions requires allele-specific genome editing, but the use of CRISPR for this purpose has not b...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964623/ https://www.ncbi.nlm.nih.gov/pubmed/27465215 http://dx.doi.org/10.1038/srep30485 |