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Heterogeneity and proliferation of invasive cancer subclones in game theory models of the Warburg effect
OBJECTIVES: The Warburg effect, a switch from aerobic energy production to anaerobic glycolysis, promotes tumour proliferation and motility by inducing acidification of the tumour microenvironment. Therapies that reduce acidity could impair tumour growth and invasiveness. I analysed the dynamics of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964921/ https://www.ncbi.nlm.nih.gov/pubmed/25643821 http://dx.doi.org/10.1111/cpr.12169 |