Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury

BACKGROUND: Ischemia/reperfusion (I/R) is an important cause of acute renal failure and delayed graft function, and it may induce chronic renal damage by activating epithelial to mesenchymal transition (EMT) of renal tubular cells. Heparanase (HPSE), an endoglycosidase that regulates FGF-2 and TGFβ-...

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Detalles Bibliográficos
Autores principales: Masola, Valentina, Zaza, Gianluigi, Gambaro, Giovanni, Onisto, Maurizio, Bellin, Gloria, Vischini, Gisella, Khamaysi, Iyad, Hassan, Ahmad, Hamoud, Shadi, Nativ, Omri, N. Heyman, Samuel, Lupo, Antonio, Vlodavsky, Israel, Abassi, Zaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965068/
https://www.ncbi.nlm.nih.gov/pubmed/27467172
http://dx.doi.org/10.1371/journal.pone.0160074

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