Transcriptional Bursting Explains the Noise–Versus–Mean Relationship in mRNA and Protein Levels

Recent analysis demonstrates that the HIV-1 Long Terminal Repeat (HIV LTR) promoter exhibits a range of possible transcriptional burst sizes and frequencies for any mean-expression level. However, these results have also been interpreted as demonstrating that cell-to-cell expression variability (noi...

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Detalles Bibliográficos
Autores principales: Dar, Roy D., Shaffer, Sydney M., Singh, Abhyudai, Razooky, Brandon S., Simpson, Michael L., Raj, Arjun, Weinberger, Leor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965078/
https://www.ncbi.nlm.nih.gov/pubmed/27467384
http://dx.doi.org/10.1371/journal.pone.0158298

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