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Competitive Fitness of Influenza B Viruses Possessing E119A and H274Y Neuraminidase Inhibitor Resistance–Associated Substitutions in Ferrets
Neuraminidase (NA) inhibitors (NAIs) are the only antiviral drugs recommended for influenza treatment and prophylaxis. Although NAI-resistant influenza B viruses that could pose a threat to public health have been reported in the field, their fitness is poorly understood. We evaluated in ferrets the...
Autores principales: | Pascua, Philippe Noriel Q., Marathe, Bindumadhav M., Burnham, Andrew J., Vogel, Peter, Webby, Richard J., Webster, Robert G., Govorkova, Elena A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965113/ https://www.ncbi.nlm.nih.gov/pubmed/27466813 http://dx.doi.org/10.1371/journal.pone.0159847 |
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