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Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons

Metformin is a widely prescribed drug used to treat type-2 diabetes, although recent studies show it has wide ranging effects to treat other diseases. Animal and retrospective human studies indicate that Metformin treatment is neuroprotective in Parkinson’s Disease (PD), although the neuroprotective...

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Detalles Bibliográficos
Autores principales:	Bayliss, Jacqueline A., Lemus, Moyra B., Santos, Vanessa V., Deo, Minh, Davies, Jeffrey S., Kemp, Bruce E., Elsworth, John D., Andrews, Zane B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965122/ https://www.ncbi.nlm.nih.gov/pubmed/27467571 http://dx.doi.org/10.1371/journal.pone.0159381

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