Reducing Both Pgp Overexpression and Drug Efflux with Anti-Cancer Gold-Paclitaxel Nanoconjugates

Repeated administrations of anti-cancer drugs to patients often induce drug resistance. P-glycoprotein (Pgp) facilitates an efficient drug efflux, preventing cellular accumulation of drugs and causing multi-drug resistance (MDR). In this study, we developed a gold-paclitaxel nanoconjugate system to...

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Detalles Bibliográficos
Autores principales: Li, Fei, Zhou, Xiaofei, Zhou, Hongyu, Jia, Jianbo, Li, Liwen, Zhai, Shumei, Yan, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965149/
https://www.ncbi.nlm.nih.gov/pubmed/27467397
http://dx.doi.org/10.1371/journal.pone.0160042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965149/
https://www.ncbi.nlm.nih.gov/pubmed/27467397
http://dx.doi.org/10.1371/journal.pone.0160042

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