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Deletion of Angiotensin II Type 2 Receptor Accelerates Adipogenesis in Murine Mesenchymal Stem Cells via Wnt10b/beta-catenin Signaling
Recent evidence suggests that the renin-angiotensin system (RAS) plays a vital role in adipocyte biology and the pathophysiology of metabolic syndrome. Obesity is the main culprit of metabolic syndrome and mesenchymal stem cells (MSCs) have been forwarded as a major source of adipocyte generation. P...
Autores principales: | Matsushita, Kenichi, Wu, Yaojiong, Pratt, Richard E, Dzau, Victor J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965305/ https://www.ncbi.nlm.nih.gov/pubmed/27295344 http://dx.doi.org/10.1038/labinvest.2016.66 |
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