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Allele-Specific Quantification of Structural Variations in Cancer Genomes
Aneuploidy and structural variations (SVs) generate cancer genomes containing a mixture of rearranged genomic segments with extensive somatic copy number alterations. However, existing methods can identify either SVs or allele-specific copy number alterations, but not both simultaneously, which prov...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965314/ https://www.ncbi.nlm.nih.gov/pubmed/27453446 http://dx.doi.org/10.1016/j.cels.2016.05.007 |