Cargando…
Identification of clinically achievable combination therapies in childhood rhabdomyosarcoma
PURPOSE: Systemic therapy has improved rhabdomyosarcoma event-free and overall survival; however, approximately 40 % of patients will have progressive or recurrent disease which is difficult to cure and remains a considerable challenge. Minimal progress has been made in improving outcomes for metast...
Autores principales: | Kahen, Elliot, Yu, Diana, Harrison, Douglas J., Clark, Justine, Hingorani, Pooja, Cubitt, Christopher L., Reed, Damon R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965487/ https://www.ncbi.nlm.nih.gov/pubmed/27324022 http://dx.doi.org/10.1007/s00280-016-3077-8 |
Ejemplares similares
-
Identification of Synergistic, Clinically Achievable, Combination Therapies for Osteosarcoma
por: Yu, Diana, et al.
Publicado: (2015) -
Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines
por: Welch, Darcy, et al.
Publicado: (2019) -
Neurofibromin level directs RAS pathway signaling and mediates sensitivity to targeted agents in malignant peripheral nerve sheath tumors
por: Kahen, Elliot John, et al.
Publicado: (2018) -
The genomic landscape of malignant peripheral nerve sheath tumors: diverse drivers of Ras pathway activation
por: Brohl, Andrew S., et al.
Publicado: (2017) -
Rapid Screening of Novel Agents for Combination Therapy in Sarcomas
por: Cubitt, Christopher L., et al.
Publicado: (2013)