Coexistence of Acute Crescent Glomerulonephritis and IgG4-Related Kidney Disease

INTRODUCTION: IgG4-related disease (IgG4-RD) is a fibroinflammatory disorder that may involve almost each organ or system. IgG4-related kidney disease (IgG4-RKD) refers to renal lesions associated with IgG4-RD. The most frequent morphological type of renal lesions is IgG4-related tubulointerstitial...

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Autores principales: Lu, Zeyuan, Yin, Jianyong, Bao, Hongda, Jiao, Qiong, Wu, Huijuan, Wu, Rui, Xue, Qin, Wang, Niansong, Zhang, Zhigang, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965529/
https://www.ncbi.nlm.nih.gov/pubmed/27504450
http://dx.doi.org/10.1159/000448025
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author Lu, Zeyuan
Yin, Jianyong
Bao, Hongda
Jiao, Qiong
Wu, Huijuan
Wu, Rui
Xue, Qin
Wang, Niansong
Zhang, Zhigang
Wang, Feng
author_facet Lu, Zeyuan
Yin, Jianyong
Bao, Hongda
Jiao, Qiong
Wu, Huijuan
Wu, Rui
Xue, Qin
Wang, Niansong
Zhang, Zhigang
Wang, Feng
author_sort Lu, Zeyuan
collection PubMed
description INTRODUCTION: IgG4-related disease (IgG4-RD) is a fibroinflammatory disorder that may involve almost each organ or system. IgG4-related kidney disease (IgG4-RKD) refers to renal lesions associated with IgG4-RD. The most frequent morphological type of renal lesions is IgG4-related tubulointerstitial nephritis (IgG4-TIN) which is associated with increased IgG4-positive plasma cell infiltration and interstitial fibrosis. CASE REPORT: Herein, we present a rare case with coexisting IgG4-RKD and acute crescent glomerulonephritis with concomitant severe tubulointerstitial lesions instead of classic IgG4-TIN. CONCLUSION: IgG4-RKD and acute crescent glomerulonephritis can occur in the same patient. This case may give us a clearer viewpoint of the disease.
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spelling pubmed-49655292016-08-08 Coexistence of Acute Crescent Glomerulonephritis and IgG4-Related Kidney Disease Lu, Zeyuan Yin, Jianyong Bao, Hongda Jiao, Qiong Wu, Huijuan Wu, Rui Xue, Qin Wang, Niansong Zhang, Zhigang Wang, Feng Case Rep Nephrol Dial Case Report INTRODUCTION: IgG4-related disease (IgG4-RD) is a fibroinflammatory disorder that may involve almost each organ or system. IgG4-related kidney disease (IgG4-RKD) refers to renal lesions associated with IgG4-RD. The most frequent morphological type of renal lesions is IgG4-related tubulointerstitial nephritis (IgG4-TIN) which is associated with increased IgG4-positive plasma cell infiltration and interstitial fibrosis. CASE REPORT: Herein, we present a rare case with coexisting IgG4-RKD and acute crescent glomerulonephritis with concomitant severe tubulointerstitial lesions instead of classic IgG4-TIN. CONCLUSION: IgG4-RKD and acute crescent glomerulonephritis can occur in the same patient. This case may give us a clearer viewpoint of the disease. S. Karger AG 2016-07-19 /pmc/articles/PMC4965529/ /pubmed/27504450 http://dx.doi.org/10.1159/000448025 Text en Copyright © 2016 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Lu, Zeyuan
Yin, Jianyong
Bao, Hongda
Jiao, Qiong
Wu, Huijuan
Wu, Rui
Xue, Qin
Wang, Niansong
Zhang, Zhigang
Wang, Feng
Coexistence of Acute Crescent Glomerulonephritis and IgG4-Related Kidney Disease
title Coexistence of Acute Crescent Glomerulonephritis and IgG4-Related Kidney Disease
title_full Coexistence of Acute Crescent Glomerulonephritis and IgG4-Related Kidney Disease
title_fullStr Coexistence of Acute Crescent Glomerulonephritis and IgG4-Related Kidney Disease
title_full_unstemmed Coexistence of Acute Crescent Glomerulonephritis and IgG4-Related Kidney Disease
title_short Coexistence of Acute Crescent Glomerulonephritis and IgG4-Related Kidney Disease
title_sort coexistence of acute crescent glomerulonephritis and igg4-related kidney disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965529/
https://www.ncbi.nlm.nih.gov/pubmed/27504450
http://dx.doi.org/10.1159/000448025
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