miR-30 Family Controls Proliferation and Differentiation of Intestinal Epithelial Cell Models by Directing a Broad Gene Expression Program That Includes SOX9 and the Ubiquitin Ligase Pathway

Proliferation and differentiation of intestinal epithelial cells (IECs) occur in part through precise regulation of key transcription factors, such as SOX9. MicroRNAs (miRNAs) have emerged as prominent fine-tuners of transcription factor expression and activity. We hypothesized that miRNAs, in part...

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Detalles Bibliográficos
Autores principales: Peck, Bailey C. E., Sincavage, John, Feinstein, Sydney, Mah, Amanda T., Simmons, James G., Lund, P. Kay, Sethupathy, Praveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Gene Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965549/
https://www.ncbi.nlm.nih.gov/pubmed/27261459
http://dx.doi.org/10.1074/jbc.M116.733733

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