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Simulated single molecule microscopy with SMeagol

Summary: SMeagol is a software tool to simulate highly realistic microscopy data based on spatial systems biology models, in order to facilitate development, validation and optimization of advanced analysis methods for live cell single molecule microscopy data. Availability and implementation: SMeag...

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Detalles Bibliográficos
Autores principales: Lindén, Martin, Ćurić, Vladimir, Boucharin, Alexis, Fange, David, Elf, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965627/
https://www.ncbi.nlm.nih.gov/pubmed/27153711
http://dx.doi.org/10.1093/bioinformatics/btw109
Descripción
Sumario:Summary: SMeagol is a software tool to simulate highly realistic microscopy data based on spatial systems biology models, in order to facilitate development, validation and optimization of advanced analysis methods for live cell single molecule microscopy data. Availability and implementation: SMeagol runs on Matlab R2014 and later, and uses compiled binaries in C for reaction–diffusion simulations. Documentation, source code and binaries for Mac OS, Windows and Ubuntu Linux can be downloaded from http://smeagol.sourceforge.net. Contact: johan.elf@icm.uu.se Supplementary information: Supplementary data are available at Bioinformatics online.