Predictive Validity of Some Common Animal Models of Bipolar Disorder Using Lithium and Lamotrigine Therapy: An Attempt towards a Battery-Based Approach for the Evaluation of Mood Stabilizers

OBJECTIVE: To determine the predictive validity of some of the commonly employed models of mania and depression using standard drugs i.e. lithium (70 mg/kg) and lamotrigine (5 mg/kg) in male Wistar rats. METHODS: The depression facet of bipolar disorder was evaluated using forced swim test, tail sus...

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Detalles Bibliográficos
Autores principales: Kumar, Manu, Tripathi, Chakra Dhar, Verma, Veena, Padhy, Biswa Mohan, Meshram, Girish Gulab, Abhilash, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neuropsychiatric Association 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965654/
https://www.ncbi.nlm.nih.gov/pubmed/27482245
http://dx.doi.org/10.4306/pi.2016.13.4.434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965654/
https://www.ncbi.nlm.nih.gov/pubmed/27482245
http://dx.doi.org/10.4306/pi.2016.13.4.434

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