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Hypomethylation coordinates antagonistically with hypermethylation in cancer development: a case study of leukemia
BACKGROUND: Methylation changes are frequent in cancers, but understanding how hyper- and hypomethylated region changes coordinate, associate with genomic features, and affect gene expression is needed to better understand their biological significance. The functional significance of hypermethylatio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965721/ https://www.ncbi.nlm.nih.gov/pubmed/27461342 http://dx.doi.org/10.1186/s40246-016-0071-5 |