Cargando…

Gold Nanoparticle–Mediated Targeted Delivery of Recombinant Human Endostatin Normalizes Tumour Vasculature and Improves Cancer Therapy

Tumour vasculature is generally disordered because of the production of excessive angiogenic factors by tumour cells, which results in tumour progression and reduces the effectiveness of radiotherapy or chemotherapy. Transient anti-angiogenic therapies that regulate tumour vascular morphology and fu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Wei, Zhao, Xiaoxu, Du, Bin, Li, Xin, Liu, Shuhao, Yang, Xiao-Yan, Ding, Hui, Yang, Wende, Pan, Fan, Wu, Xiaobo, Qin, Li, Pan, Yunlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965746/ https://www.ncbi.nlm.nih.gov/pubmed/27470938 http://dx.doi.org/10.1038/srep30619

Ejemplares similares

Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial–mesenchymal transition inhibition
por: Li, Wei, et al.
Publicado: (2017)

Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels
por: Zhao, Xiaoxu, et al.
Publicado: (2018)

TSP-1 as a novel biological marker of tumor vasculature normalization in colon carcinoma induced by Endostar
por: Yang, Wende, et al.
Publicado: (2020)

Recombinant human endostatin enhances the radioresponse in esophageal squamous cell carcinoma by normalizing tumor vasculature and reducing hypoxia
por: Zhu, Hongcheng, et al.
Publicado: (2015)

Recombinant Human Endostatin Normalizes Tumor Vasculature and Enhances Radiation Response in Xenografted Human Nasopharyngeal Carcinoma Models
por: Peng, Fang, et al.
Publicado: (2012)

Anterior gradient 2 as a supervisory marker for tumor vessel normalization induced by anti-angiogenic treatment
por: Pan, Fan, et al.
Publicado: (2018)

Epirubicin-gold nanoparticles suppress hepatocellular carcinoma xenograft growth in nude mice
por: Meng, William C. S., et al.
Publicado: (2015)

Clinical evaluation of vascular normalization induced by recombinant human endostatin in nasopharyngeal carcinoma via dynamic contrast-enhanced ultrasonography
por: Yang, Zhendong, et al.
Publicado: (2018)

Antiangiogenic effects of recombinant human endostatin in lung cancers
por: He, Lang, et al.
Publicado: (2018)

The accumulation of macrophages attenuates the effect of recombinant human endostatin on lung cancer
por: Liu, Yanyang, et al.
Publicado: (2016)

Current Status and Study Progress of Recombinant Human Endostatin in Cancer Treatment
por: Li, Kai, et al.
Publicado: (2018)

Gold Nanoparticles: Construction for Drug Delivery and Application in Cancer Immunotherapy
por: Huang, Huiqun, et al.
Publicado: (2023)

Tumor Vasculature Targeted Photodynamic Therapy for Enhanced Delivery of Nanoparticles
por: Zhen, Zipeng, et al.
Publicado: (2014)

Zebrafish functional xenograft vasculature platform identifies PF-502 as a durable vasculature normalization drug
por: Zhong, Jian, et al.
Publicado: (2023)

Co-delivery of docetaxel and endostatin by a biodegradable nanoparticle for the synergistic treatment of cervical cancer
por: Qiu, Bo, et al.
Publicado: (2012)

Tuning Payload Delivery in Tumour Cylindroids using Gold Nanoparticles
por: Kim, Byoungjin, et al.
Publicado: (2010)

Clinical effects of cisplatin plus recombinant human endostatin (rh-endostatin) intratumoral injection on malignant central airway obstruction: a retrospective analysis of 319 cases
por: Zhou, Yunzhi, et al.
Publicado: (2021)

Endostatin in the pancreas
por: Wigmore, S J
Publicado: (2005)

Recombinant human endostatin in combination with CHOP regimen for peripheral T cell lymphoma
por: Zhang, Qunling, et al.
Publicado: (2016)

Recombinant human endostatin combined with radiotherapy inhibits colorectal cancer growth
por: Zhang, Ke, et al.
Publicado: (2017)

Preparation of endostatin-loaded chitosan nanoparticles and evaluation of the antitumor effect of such nanoparticles on the Lewis lung cancer model
por: Ding, Rui-Lin, et al.
Publicado: (2017)

Comparisons of biophysical properties and bioactivities of mono-PEGylated endostatin and an endostatin analog
por: Wang, Shan, et al.
Publicado: (2016)

Label-Free Visualization and Tracking of Gold Nanoparticles in Vasculature Using Multiphoton Luminescence
por: Burkitt, Sean, et al.
Publicado: (2020)

Recombined humanized endostatin (Endostar) combined with chemotherapy for advanced bone and soft tissue sarcomas in stage IV
por: Xing, Peipei, et al.
Publicado: (2016)

JP1 normalizes tumor vasculature to suppress metastasis and facilitate drug delivery by inhibiting IL-8
por: Cui, Jiahua, et al.
Publicado: (2023)

Recombinant human endostatin combined with chemotherapy for advanced squamous cell lung cancer: a meta-analysis
por: Feng, Li, et al.
Publicado: (2021)

Autoantibodies to endostatin in patients with breast cancer: correlation to endostatin levels and clinical outcome
por: Bachelot, T, et al.
Publicado: (2006)

In vivo antitumor effect of endostatin-loaded chitosan nanoparticles combined with paclitaxel on Lewis lung carcinoma
por: Xie, Fang, et al.
Publicado: (2017)

Recombined humanized endostatin (Endostar) intravenous infusion in the treatment of refractory nasopharyngeal carcinoma: Three case reports
por: Chen, Chen, et al.
Publicado: (2019)

Inhibitory effect of endostatin gene therapy combined with phosphorus-32 colloid on tumour growth in Wistar rats
por: Gao, Huiqi, et al.
Publicado: (2016)

The mechanistic immunosuppressive role of the tumour vasculature and potential nanoparticle-mediated therapeutic strategies
por: Ileiwat, Zakaria Elias, et al.
Publicado: (2022)

Chemotherapy Combined With Recombinant Human Endostatin (Endostar) Significantly Improves the Progression-Free Survival of Stage IV Soft Tissue Sarcomas
por: Liao, Zhichao, et al.
Publicado: (2022)

Enhancement of Recombinant Human Endostatin on the Radiosensitivity of Human Pulmonary Adenocarcinoma A549 Cells and Its Mechanism
por: Jiang, Xiao-dong, et al.
Publicado: (2012)

Comparison of the antiangiogenic activity of modified RGDRGD-endostatin to endostatin delivered by gene transfer in vivo rabbit neovascularization model
por: Ge, Hong-yan, et al.
Publicado: (2011)

Recombined humanized endostatin‐induced suppression of HMGB1 expression inhibits proliferation of NSCLC cancer cells
por: Meng, Fan‐Jie, et al.
Publicado: (2018)

Combining therapy with recombinant human endostatin and cytotoxic agents for recurrent disseminated glioblastoma: a retrospective study
por: Ge, Jing-jing, et al.
Publicado: (2020)

Recombinant Human Endostatin Endostar Suppresses Angiogenesis and Lymphangiogenesis of Malignant Pleural Effusion in Mice
por: Ma, Xingqun, et al.
Publicado: (2012)

The Challenges of Recombinant Endostatin in Clinical Application: Focus on the Different Expression Systems and Molecular Bioengineering
por: Mohajeri, Abbas, et al.
Publicado: (2017)

Recombinant Endostatin as a Potential Radiosensitizer in the Treatment of Non-Small Cell Lung Cancer
por: Cunningham, Charnay, et al.
Publicado: (2023)

Tumor vasculature is a key determinant for the efficiency of nanoparticle-mediated siRNA delivery
por: Li, L, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_iqqhbiv48jjoqllb8a7t48k54b