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Pyruvate dehydrogenase kinase regulates hepatitis C virus replication

During replication, hepatitis C virus (HCV) utilizes macromolecules produced by its host cell. This process requires host cellular metabolic reprogramming to favor elevated levels of aerobic glycolysis. Therefore, we evaluated whether pyruvate dehydrogenase kinase (PDK), a mitochondrial enzyme that...

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Detalles Bibliográficos
Autores principales: Jung, Gwon-Soo, Jeon, Jae-Han, Choi, Yeon-Kyung, Jang, Se Young, Park, Soo Young, Kim, Sung-Woo, Byun, Jun-Kyu, Kim, Mi-Kyung, Lee, Sungwoo, Shin, Eui-Cheol, Lee, In-Kyu, Kang, Yu Na, Park, Keun-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965757/
https://www.ncbi.nlm.nih.gov/pubmed/27471054
http://dx.doi.org/10.1038/srep30846