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Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice

The transcription factor Keap1-Nrf2 system plays a key role in inflammation which is involved in depression. We found lower expression of Keap1 and Nrf2 proteins in the prefrontal cortex (PFC), CA3 and dentate gyrus (DG) of hippocampus in mice with depression-like phenotype compared to control mice....

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Detalles Bibliográficos
Autores principales: Yao, Wei, Zhang, Ji-chun, Ishima, Tamaki, Dong, Chao, Yang, Chun, Ren, Qian, Ma, Min, Han, Mei, Wu, Jin, Suganuma, Hiroyuki, Ushida, Yusuke, Yamamoto, Masayuki, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965765/
https://www.ncbi.nlm.nih.gov/pubmed/27470577
http://dx.doi.org/10.1038/srep30659

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