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Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice
The transcription factor Keap1-Nrf2 system plays a key role in inflammation which is involved in depression. We found lower expression of Keap1 and Nrf2 proteins in the prefrontal cortex (PFC), CA3 and dentate gyrus (DG) of hippocampus in mice with depression-like phenotype compared to control mice....
Autores principales: | Yao, Wei, Zhang, Ji-chun, Ishima, Tamaki, Dong, Chao, Yang, Chun, Ren, Qian, Ma, Min, Han, Mei, Wu, Jin, Suganuma, Hiroyuki, Ushida, Yusuke, Yamamoto, Masayuki, Hashimoto, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965765/ https://www.ncbi.nlm.nih.gov/pubmed/27470577 http://dx.doi.org/10.1038/srep30659 |
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