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High resolution iridocorneal angle imaging system by axicon lens assisted gonioscopy
Direct visualization and assessment of the iridocorneal angle (ICA) region with high resolution is important for the clinical evaluation of glaucoma. However, the current clinical imaging systems for ICA do not provide sufficient structural details due to their poor resolution. The key challenges in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965779/ https://www.ncbi.nlm.nih.gov/pubmed/27471000 http://dx.doi.org/10.1038/srep30844 |
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author | Perinchery, Sandeep Menon Shinde, Anant Fu, Chan Yiu Jeesmond Hong, Xun Jie Baskaran, Mani Aung, Tin Murukeshan, Vadakke Matham |
author_facet | Perinchery, Sandeep Menon Shinde, Anant Fu, Chan Yiu Jeesmond Hong, Xun Jie Baskaran, Mani Aung, Tin Murukeshan, Vadakke Matham |
author_sort | Perinchery, Sandeep Menon |
collection | PubMed |
description | Direct visualization and assessment of the iridocorneal angle (ICA) region with high resolution is important for the clinical evaluation of glaucoma. However, the current clinical imaging systems for ICA do not provide sufficient structural details due to their poor resolution. The key challenges in achieving high quality ICA imaging are its location in the anterior region of the eye and the occurrence of total internal reflection due to refractive index difference between cornea and air. Here, we report an indirect axicon assisted gonioscopy imaging probe with white light illumination. The illustrated results with this probe shows significantly improved visualization of structures in the ICA including TM region, compared to the current available tools. It could reveal critical details of ICA and expected to aid management by providing information that is complementary to angle photography and gonioscopy. |
format | Online Article Text |
id | pubmed-4965779 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-49657792016-08-08 High resolution iridocorneal angle imaging system by axicon lens assisted gonioscopy Perinchery, Sandeep Menon Shinde, Anant Fu, Chan Yiu Jeesmond Hong, Xun Jie Baskaran, Mani Aung, Tin Murukeshan, Vadakke Matham Sci Rep Article Direct visualization and assessment of the iridocorneal angle (ICA) region with high resolution is important for the clinical evaluation of glaucoma. However, the current clinical imaging systems for ICA do not provide sufficient structural details due to their poor resolution. The key challenges in achieving high quality ICA imaging are its location in the anterior region of the eye and the occurrence of total internal reflection due to refractive index difference between cornea and air. Here, we report an indirect axicon assisted gonioscopy imaging probe with white light illumination. The illustrated results with this probe shows significantly improved visualization of structures in the ICA including TM region, compared to the current available tools. It could reveal critical details of ICA and expected to aid management by providing information that is complementary to angle photography and gonioscopy. Nature Publishing Group 2016-07-29 /pmc/articles/PMC4965779/ /pubmed/27471000 http://dx.doi.org/10.1038/srep30844 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Perinchery, Sandeep Menon Shinde, Anant Fu, Chan Yiu Jeesmond Hong, Xun Jie Baskaran, Mani Aung, Tin Murukeshan, Vadakke Matham High resolution iridocorneal angle imaging system by axicon lens assisted gonioscopy |
title | High resolution iridocorneal angle imaging system by axicon lens assisted gonioscopy |
title_full | High resolution iridocorneal angle imaging system by axicon lens assisted gonioscopy |
title_fullStr | High resolution iridocorneal angle imaging system by axicon lens assisted gonioscopy |
title_full_unstemmed | High resolution iridocorneal angle imaging system by axicon lens assisted gonioscopy |
title_short | High resolution iridocorneal angle imaging system by axicon lens assisted gonioscopy |
title_sort | high resolution iridocorneal angle imaging system by axicon lens assisted gonioscopy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965779/ https://www.ncbi.nlm.nih.gov/pubmed/27471000 http://dx.doi.org/10.1038/srep30844 |
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