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A new in vitro hemagglutinin inhibitor screening system based on a single-vesicle fusion assay

Hemagglutinin (HA) from the influenza virus plays a pivotal role in the infection of host mammalian cells and is, therefore, a druggable target, similar to neuraminidase. However, research involving the influenza virus must be conducted in facilities certified at or above Biosafety Level 2 because o...

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Detalles Bibliográficos
Autores principales: Lee, Hanki, Jin, Wook, Jeong, Byeong-Chul, Suh, Joo-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965830/
https://www.ncbi.nlm.nih.gov/pubmed/27469068
http://dx.doi.org/10.1038/srep30642