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Reconstitution and Functional Analysis of a Full-Length Hepatitis C Virus NS5B Polymerase on a Supported Lipid Bilayer

[Image: see text] Therapeutic targeting of membrane-associated viral proteins is complicated by the challenge of investigating their enzymatic activities in the native membrane-bound state. To permit functional characterization of these proteins, we hypothesized that the supported lipid bilayer (SLB...

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Detalles Bibliográficos
Autores principales:	Cho, Nam-Joon, Pham, Edward A., Hagey, Rachel J., Lévêque, Vincent J., Ma, Han, Klumpp, Klaus, Glenn, Jeffrey S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2016
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965852/ https://www.ncbi.nlm.nih.gov/pubmed/27504492 http://dx.doi.org/10.1021/acscentsci.6b00112

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