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Accelerating degradation rate of pure iron by zinc ion implantation

Pure iron has been considered as a promising candidate for biodegradable implant applications. However, a faster degradation rate of pure iron is needed to meet the clinical requirement. In this work, metal vapor vacuum arc technology was adopted to implant zinc ions into the surface of pure iron. R...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Zheng, Yufeng, Han, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966292/
https://www.ncbi.nlm.nih.gov/pubmed/27482462
http://dx.doi.org/10.1093/rb/rbw020
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author Huang, Tao
Zheng, Yufeng
Han, Yong
author_facet Huang, Tao
Zheng, Yufeng
Han, Yong
author_sort Huang, Tao
collection PubMed
description Pure iron has been considered as a promising candidate for biodegradable implant applications. However, a faster degradation rate of pure iron is needed to meet the clinical requirement. In this work, metal vapor vacuum arc technology was adopted to implant zinc ions into the surface of pure iron. Results showed that the implantation depth of zinc ions was about 60 nm. The degradation rate of pure iron was found to be accelerated after zinc ion implantation. The cytotoxicity tests revealed that the implanted zinc ions brought a slight increase on cytotoxicity of the tested cells. In terms of hemocompatibility, the hemolysis of zinc ion implanted pure iron was lower than 2%. However, zinc ions might induce more adhered and activated platelets on the surface of pure iron. Overall, zinc ion implantation can be a feasible way to accelerate the degradation rate of pure iron for biodegradable applications.
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spelling pubmed-49662922016-08-01 Accelerating degradation rate of pure iron by zinc ion implantation Huang, Tao Zheng, Yufeng Han, Yong Regen Biomater Research Articles Pure iron has been considered as a promising candidate for biodegradable implant applications. However, a faster degradation rate of pure iron is needed to meet the clinical requirement. In this work, metal vapor vacuum arc technology was adopted to implant zinc ions into the surface of pure iron. Results showed that the implantation depth of zinc ions was about 60 nm. The degradation rate of pure iron was found to be accelerated after zinc ion implantation. The cytotoxicity tests revealed that the implanted zinc ions brought a slight increase on cytotoxicity of the tested cells. In terms of hemocompatibility, the hemolysis of zinc ion implanted pure iron was lower than 2%. However, zinc ions might induce more adhered and activated platelets on the surface of pure iron. Overall, zinc ion implantation can be a feasible way to accelerate the degradation rate of pure iron for biodegradable applications. Oxford University Press 2016-12 2016-06-05 /pmc/articles/PMC4966292/ /pubmed/27482462 http://dx.doi.org/10.1093/rb/rbw020 Text en © The Author(s) 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Huang, Tao
Zheng, Yufeng
Han, Yong
Accelerating degradation rate of pure iron by zinc ion implantation
title Accelerating degradation rate of pure iron by zinc ion implantation
title_full Accelerating degradation rate of pure iron by zinc ion implantation
title_fullStr Accelerating degradation rate of pure iron by zinc ion implantation
title_full_unstemmed Accelerating degradation rate of pure iron by zinc ion implantation
title_short Accelerating degradation rate of pure iron by zinc ion implantation
title_sort accelerating degradation rate of pure iron by zinc ion implantation
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966292/
https://www.ncbi.nlm.nih.gov/pubmed/27482462
http://dx.doi.org/10.1093/rb/rbw020
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