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Accelerating degradation rate of pure iron by zinc ion implantation
Pure iron has been considered as a promising candidate for biodegradable implant applications. However, a faster degradation rate of pure iron is needed to meet the clinical requirement. In this work, metal vapor vacuum arc technology was adopted to implant zinc ions into the surface of pure iron. R...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966292/ https://www.ncbi.nlm.nih.gov/pubmed/27482462 http://dx.doi.org/10.1093/rb/rbw020 |
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author | Huang, Tao Zheng, Yufeng Han, Yong |
author_facet | Huang, Tao Zheng, Yufeng Han, Yong |
author_sort | Huang, Tao |
collection | PubMed |
description | Pure iron has been considered as a promising candidate for biodegradable implant applications. However, a faster degradation rate of pure iron is needed to meet the clinical requirement. In this work, metal vapor vacuum arc technology was adopted to implant zinc ions into the surface of pure iron. Results showed that the implantation depth of zinc ions was about 60 nm. The degradation rate of pure iron was found to be accelerated after zinc ion implantation. The cytotoxicity tests revealed that the implanted zinc ions brought a slight increase on cytotoxicity of the tested cells. In terms of hemocompatibility, the hemolysis of zinc ion implanted pure iron was lower than 2%. However, zinc ions might induce more adhered and activated platelets on the surface of pure iron. Overall, zinc ion implantation can be a feasible way to accelerate the degradation rate of pure iron for biodegradable applications. |
format | Online Article Text |
id | pubmed-4966292 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-49662922016-08-01 Accelerating degradation rate of pure iron by zinc ion implantation Huang, Tao Zheng, Yufeng Han, Yong Regen Biomater Research Articles Pure iron has been considered as a promising candidate for biodegradable implant applications. However, a faster degradation rate of pure iron is needed to meet the clinical requirement. In this work, metal vapor vacuum arc technology was adopted to implant zinc ions into the surface of pure iron. Results showed that the implantation depth of zinc ions was about 60 nm. The degradation rate of pure iron was found to be accelerated after zinc ion implantation. The cytotoxicity tests revealed that the implanted zinc ions brought a slight increase on cytotoxicity of the tested cells. In terms of hemocompatibility, the hemolysis of zinc ion implanted pure iron was lower than 2%. However, zinc ions might induce more adhered and activated platelets on the surface of pure iron. Overall, zinc ion implantation can be a feasible way to accelerate the degradation rate of pure iron for biodegradable applications. Oxford University Press 2016-12 2016-06-05 /pmc/articles/PMC4966292/ /pubmed/27482462 http://dx.doi.org/10.1093/rb/rbw020 Text en © The Author(s) 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Huang, Tao Zheng, Yufeng Han, Yong Accelerating degradation rate of pure iron by zinc ion implantation |
title | Accelerating degradation rate of pure iron by zinc ion implantation |
title_full | Accelerating degradation rate of pure iron by zinc ion implantation |
title_fullStr | Accelerating degradation rate of pure iron by zinc ion implantation |
title_full_unstemmed | Accelerating degradation rate of pure iron by zinc ion implantation |
title_short | Accelerating degradation rate of pure iron by zinc ion implantation |
title_sort | accelerating degradation rate of pure iron by zinc ion implantation |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966292/ https://www.ncbi.nlm.nih.gov/pubmed/27482462 http://dx.doi.org/10.1093/rb/rbw020 |
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