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Spindle cell carcinoma of the conjunctiva: A rare entity

An 85-year-old male presented with painless bulging lesion over the cornea. Clinical history, diagnostic imaging studies, and histopathologic sections were evaluated. The patient clinically displayed an vascularized conjunctival lesion located at the superior bulbar conjunctiva with extension onto c...

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Autores principales: Coban-Karatas, Muge, Bal, Nebil, Altan-Yaycioğlu, Rana, Terzi, Aysen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966383/
https://www.ncbi.nlm.nih.gov/pubmed/27380985
http://dx.doi.org/10.4103/0301-4738.185630
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author Coban-Karatas, Muge
Bal, Nebil
Altan-Yaycioğlu, Rana
Terzi, Aysen
author_facet Coban-Karatas, Muge
Bal, Nebil
Altan-Yaycioğlu, Rana
Terzi, Aysen
author_sort Coban-Karatas, Muge
collection PubMed
description An 85-year-old male presented with painless bulging lesion over the cornea. Clinical history, diagnostic imaging studies, and histopathologic sections were evaluated. The patient clinically displayed an vascularized conjunctival lesion located at the superior bulbar conjunctiva with extension onto cornea covering 2/3 of his pupillary aperture superiorly. His visual acuity was counting fingers at 4 m. The patient underwent a total excision of the lesion including conjunctival and corneal parts. Histopathologic evaluation revealed spindle cell carcinoma which involves the whole conjunctival squamous epithelium with significant polarity loss, nuclear enlargement with hyperchromasia and pleomorphism, and mitotic activity. Diagnosis of spindle cell carcinoma is challenging because of overlapping histopathological features with other spindle cell tumors. The detailed pathologic examination is very important for the decision of proper treatment.
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spelling pubmed-49663832016-08-10 Spindle cell carcinoma of the conjunctiva: A rare entity Coban-Karatas, Muge Bal, Nebil Altan-Yaycioğlu, Rana Terzi, Aysen Indian J Ophthalmol Brief Communications An 85-year-old male presented with painless bulging lesion over the cornea. Clinical history, diagnostic imaging studies, and histopathologic sections were evaluated. The patient clinically displayed an vascularized conjunctival lesion located at the superior bulbar conjunctiva with extension onto cornea covering 2/3 of his pupillary aperture superiorly. His visual acuity was counting fingers at 4 m. The patient underwent a total excision of the lesion including conjunctival and corneal parts. Histopathologic evaluation revealed spindle cell carcinoma which involves the whole conjunctival squamous epithelium with significant polarity loss, nuclear enlargement with hyperchromasia and pleomorphism, and mitotic activity. Diagnosis of spindle cell carcinoma is challenging because of overlapping histopathological features with other spindle cell tumors. The detailed pathologic examination is very important for the decision of proper treatment. Medknow Publications & Media Pvt Ltd 2016-05 /pmc/articles/PMC4966383/ /pubmed/27380985 http://dx.doi.org/10.4103/0301-4738.185630 Text en Copyright: © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Brief Communications
Coban-Karatas, Muge
Bal, Nebil
Altan-Yaycioğlu, Rana
Terzi, Aysen
Spindle cell carcinoma of the conjunctiva: A rare entity
title Spindle cell carcinoma of the conjunctiva: A rare entity
title_full Spindle cell carcinoma of the conjunctiva: A rare entity
title_fullStr Spindle cell carcinoma of the conjunctiva: A rare entity
title_full_unstemmed Spindle cell carcinoma of the conjunctiva: A rare entity
title_short Spindle cell carcinoma of the conjunctiva: A rare entity
title_sort spindle cell carcinoma of the conjunctiva: a rare entity
topic Brief Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966383/
https://www.ncbi.nlm.nih.gov/pubmed/27380985
http://dx.doi.org/10.4103/0301-4738.185630
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AT terziaysen spindlecellcarcinomaoftheconjunctivaarareentity