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Spindle cell carcinoma of the conjunctiva: A rare entity
An 85-year-old male presented with painless bulging lesion over the cornea. Clinical history, diagnostic imaging studies, and histopathologic sections were evaluated. The patient clinically displayed an vascularized conjunctival lesion located at the superior bulbar conjunctiva with extension onto c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966383/ https://www.ncbi.nlm.nih.gov/pubmed/27380985 http://dx.doi.org/10.4103/0301-4738.185630 |
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author | Coban-Karatas, Muge Bal, Nebil Altan-Yaycioğlu, Rana Terzi, Aysen |
author_facet | Coban-Karatas, Muge Bal, Nebil Altan-Yaycioğlu, Rana Terzi, Aysen |
author_sort | Coban-Karatas, Muge |
collection | PubMed |
description | An 85-year-old male presented with painless bulging lesion over the cornea. Clinical history, diagnostic imaging studies, and histopathologic sections were evaluated. The patient clinically displayed an vascularized conjunctival lesion located at the superior bulbar conjunctiva with extension onto cornea covering 2/3 of his pupillary aperture superiorly. His visual acuity was counting fingers at 4 m. The patient underwent a total excision of the lesion including conjunctival and corneal parts. Histopathologic evaluation revealed spindle cell carcinoma which involves the whole conjunctival squamous epithelium with significant polarity loss, nuclear enlargement with hyperchromasia and pleomorphism, and mitotic activity. Diagnosis of spindle cell carcinoma is challenging because of overlapping histopathological features with other spindle cell tumors. The detailed pathologic examination is very important for the decision of proper treatment. |
format | Online Article Text |
id | pubmed-4966383 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-49663832016-08-10 Spindle cell carcinoma of the conjunctiva: A rare entity Coban-Karatas, Muge Bal, Nebil Altan-Yaycioğlu, Rana Terzi, Aysen Indian J Ophthalmol Brief Communications An 85-year-old male presented with painless bulging lesion over the cornea. Clinical history, diagnostic imaging studies, and histopathologic sections were evaluated. The patient clinically displayed an vascularized conjunctival lesion located at the superior bulbar conjunctiva with extension onto cornea covering 2/3 of his pupillary aperture superiorly. His visual acuity was counting fingers at 4 m. The patient underwent a total excision of the lesion including conjunctival and corneal parts. Histopathologic evaluation revealed spindle cell carcinoma which involves the whole conjunctival squamous epithelium with significant polarity loss, nuclear enlargement with hyperchromasia and pleomorphism, and mitotic activity. Diagnosis of spindle cell carcinoma is challenging because of overlapping histopathological features with other spindle cell tumors. The detailed pathologic examination is very important for the decision of proper treatment. Medknow Publications & Media Pvt Ltd 2016-05 /pmc/articles/PMC4966383/ /pubmed/27380985 http://dx.doi.org/10.4103/0301-4738.185630 Text en Copyright: © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Brief Communications Coban-Karatas, Muge Bal, Nebil Altan-Yaycioğlu, Rana Terzi, Aysen Spindle cell carcinoma of the conjunctiva: A rare entity |
title | Spindle cell carcinoma of the conjunctiva: A rare entity |
title_full | Spindle cell carcinoma of the conjunctiva: A rare entity |
title_fullStr | Spindle cell carcinoma of the conjunctiva: A rare entity |
title_full_unstemmed | Spindle cell carcinoma of the conjunctiva: A rare entity |
title_short | Spindle cell carcinoma of the conjunctiva: A rare entity |
title_sort | spindle cell carcinoma of the conjunctiva: a rare entity |
topic | Brief Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966383/ https://www.ncbi.nlm.nih.gov/pubmed/27380985 http://dx.doi.org/10.4103/0301-4738.185630 |
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