Nodulocystic Basal Cell Carcinoma Arising Directly from a Seborrheic Keratosis: A Rare Case Report

Seborrheic keratoses (SKs) are common epidermal tumors composed of benign keratinocytes. Malignant skin tumors including basal cell carcinoma (BCC) rarely arise within SKs. We report a rare case of an 82-year-old man with nodulocystic BCC that appeared at the center of a scaly hyperpigmented SK that...

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Autores principales: Shibao, Kana, Okiyama, Naoko, Tanaka, Ryota, Maruyama, Hitoshi, Fujisawa, Yasuhiro, Fujimoto, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966407/
https://www.ncbi.nlm.nih.gov/pubmed/27512194
http://dx.doi.org/10.4103/0019-5154.185720
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author Shibao, Kana
Okiyama, Naoko
Tanaka, Ryota
Maruyama, Hitoshi
Fujisawa, Yasuhiro
Fujimoto, Manabu
author_facet Shibao, Kana
Okiyama, Naoko
Tanaka, Ryota
Maruyama, Hitoshi
Fujisawa, Yasuhiro
Fujimoto, Manabu
author_sort Shibao, Kana
collection PubMed
description Seborrheic keratoses (SKs) are common epidermal tumors composed of benign keratinocytes. Malignant skin tumors including basal cell carcinoma (BCC) rarely arise within SKs. We report a rare case of an 82-year-old man with nodulocystic BCC that appeared at the center of a scaly hyperpigmented SK that had been presented for more than 10 years. It was histologically confirmed that CK19-positive BCC arose directly from the wall of the pseudohorn cyst, a part of the SK. Nodular and/or cystic BCC also rarely arise within SKs while the most common histologic type of BCC within SKs is the superficial type. Careful observation of SKs is important even though it is rarely a background condition for malignant transformation.
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spelling pubmed-49664072016-08-10 Nodulocystic Basal Cell Carcinoma Arising Directly from a Seborrheic Keratosis: A Rare Case Report Shibao, Kana Okiyama, Naoko Tanaka, Ryota Maruyama, Hitoshi Fujisawa, Yasuhiro Fujimoto, Manabu Indian J Dermatol Case Report Seborrheic keratoses (SKs) are common epidermal tumors composed of benign keratinocytes. Malignant skin tumors including basal cell carcinoma (BCC) rarely arise within SKs. We report a rare case of an 82-year-old man with nodulocystic BCC that appeared at the center of a scaly hyperpigmented SK that had been presented for more than 10 years. It was histologically confirmed that CK19-positive BCC arose directly from the wall of the pseudohorn cyst, a part of the SK. Nodular and/or cystic BCC also rarely arise within SKs while the most common histologic type of BCC within SKs is the superficial type. Careful observation of SKs is important even though it is rarely a background condition for malignant transformation. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4966407/ /pubmed/27512194 http://dx.doi.org/10.4103/0019-5154.185720 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Shibao, Kana
Okiyama, Naoko
Tanaka, Ryota
Maruyama, Hitoshi
Fujisawa, Yasuhiro
Fujimoto, Manabu
Nodulocystic Basal Cell Carcinoma Arising Directly from a Seborrheic Keratosis: A Rare Case Report
title Nodulocystic Basal Cell Carcinoma Arising Directly from a Seborrheic Keratosis: A Rare Case Report
title_full Nodulocystic Basal Cell Carcinoma Arising Directly from a Seborrheic Keratosis: A Rare Case Report
title_fullStr Nodulocystic Basal Cell Carcinoma Arising Directly from a Seborrheic Keratosis: A Rare Case Report
title_full_unstemmed Nodulocystic Basal Cell Carcinoma Arising Directly from a Seborrheic Keratosis: A Rare Case Report
title_short Nodulocystic Basal Cell Carcinoma Arising Directly from a Seborrheic Keratosis: A Rare Case Report
title_sort nodulocystic basal cell carcinoma arising directly from a seborrheic keratosis: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966407/
https://www.ncbi.nlm.nih.gov/pubmed/27512194
http://dx.doi.org/10.4103/0019-5154.185720
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